Angitt pris er maksimal utsalgspris fra apotek. Pakninger som selges uten resept er angitt med stjerne *. Det er fri prisfastsettelse for pakninger som selges uten resept, og maksimal utsalgspris kan derfor ikke angis.
GraviditetEn stor mengde knowledge fra gravide indikerer hverken misdannelser eller toksisitet av paracetamol hos foster/nyfødt barn. Epidemiologiske studier på nevronal utvikling hos barn eksponert for paracetamol in utero viser ikke entydige resultater. Ved langvarig behandling med kodein hos mor beneath graviditet er det sett neonatal abstinens. Det er sett neonatal respirasjonsdepresjon ved bruk av kodein ved fødsler. Paralgin forte/Paralgin key skal bare brukes beneath graviditet hvis fordel oppveier mulig risiko, og da med lavest mulig effektiv dose i kortest mulig tid og lavest mulig frekvens.
Induksjon av metabolismen av paracetamol i lever, både til inaktive metabolitter og til den levertoksiske metabolitten NAPQI.
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Sykelig forandring av leveren der det dannes bindevev i stedet for leverceller, slik at leverfunksjonen ødelegges.
Animal and scientific experiments have decided that acetaminophen has the two antipyretic and analgesic effects. This drug has actually been proven to deficiency anti-inflammatory results. Versus the salicylate drug class, acetaminophen won't disrupt tubular secretion of uric acid and doesn't have an affect on acid-foundation balance if taken on the encouraged doses.
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Legemiddel mot psykoser. I psykiatrien brukes benevnelsen antipsykotika synonymt med nevroleptika eller psykoleptika.
Maternally harmful doses which were about 7 periods the utmost advisable human dose of 360 mg/day, were associated with proof of bone resorption and incomplete bone ossification. Codeine did not reveal evidence of embrytoxicity or fetotoxicity in the rabbit design at doses around two periods the maximum proposed human dose of 360 mg/day based upon a entire body floor area comparison . Nonteratogenic outcomes
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Although potential clinical studies inspecting the final results of nursing with acetaminophen use have not been performed, acetaminophen is found secreted in human milk at small concentrations immediately after oral administration. Knowledge from over fifteen nursing mothers using acetaminophen was attained, along with the calculated every day dose of acetaminophen that reaches the toddler is about one to 2% on the maternal dose. Warning needs to be noticed when acetaminophen is taken by a nursing woman.